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UPSC Prelims 2022 Paper-1 📅 05 Jun, 2022

In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following statements:
1. The Serum Institute of India produced COVID-19 vaccine named Covishield using mRNA platform.
2. Sputnik V vaccine is manufactured using vector based platform.
3. COVAXIN is an inactivated pathogen based vaccine.

Which of the statements given above are correct?

A
(a) 1 and 2 only
B
(b) 2 and 3 only
C
(c) 1 and 3 only
D
(d) 1, 2 and 3
Result Summary
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APEDIA

UPSC Prelims
2022 • 05 Jun, 2022 • Paper-1
In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following statements:
1. The Serum Institute of India produced COVID-19 vaccine named Covishield using mRNA platform.
2. Sputnik V vaccine is manufactured using vector based platform.
3. COVAXIN is an inactivated pathogen based vaccine.

Which of the statements given above are correct?
Correct Answer
(b) 2 and 3 only
Covishield Platform: Statement 1 is factually incorrect. Covishield, manufactured by the Serum Institute of India under license from AstraZeneca, is fundamental......
Ref/Book : UPSC Prelims 2022
Ref. Subject Science & Technology
Chapter -
Ref. Topic Health & Diseases
Pg. No -
💡 Analysis & Explanation
Covishield Platform ▼
Statement 1 is factually incorrect. Covishield, manufactured by the Serum Institute of India under license from AstraZeneca, is fundamentally a viral vector vaccine (utilizing a weakened, non-replicating chimpanzee adenovirus to carry the spike protein DNA), not an mRNA vaccine like Pfizer or Moderna.
Sputnik V Platform ▼
Statement 2 is correct. The Russian-developed Sputnik V vaccine ingeniously utilizes a recombinant human adenovirus vector platform (using two different vectors) to deliver the genetic code of the SARS-CoV-2 spike protein.
Covaxin Platform ▼
Statement 3 is correct. Developed indigenously by Bharat Biotech, COVAXIN is a traditional inactivated whole virion vaccine, where the live SARS-CoV-2 virus is completely killed using chemical means so it cannot replicate, but its physical structure remains intact to safely trigger a robust immune response.
Conclusion ▼
Statements 2 and 3 correctly identify the underlying biomedical platforms of the respective vaccines.
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